Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61
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Influence of SHH/GLI1 axis on EMT mediated migration and invasion of breast cancer cells | Scientific Reports
![Figure 1 from Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding | Semantic Scholar Figure 1 from Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/ed68d4f1961459ad3c36f3641c1eb0bce3ae0389/2-Figure1-1.png)
Figure 1 from Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding | Semantic Scholar
![IJMS | Free Full-Text | GANT61 Reduces Hedgehog Molecule (GLI1) Expression and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells IJMS | Free Full-Text | GANT61 Reduces Hedgehog Molecule (GLI1) Expression and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells](https://www.mdpi.com/ijms/ijms-21-06076/article_deploy/html/images/ijms-21-06076-g009.png)
IJMS | Free Full-Text | GANT61 Reduces Hedgehog Molecule (GLI1) Expression and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells
![IJMS | Free Full-Text | Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy IJMS | Free Full-Text | Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy](https://pub.mdpi-res.com/ijms/ijms-19-02682/article_deploy/html/images/ijms-19-02682-ag.png?1570456629)
IJMS | Free Full-Text | Widespread Expression of Hedgehog Pathway Components in a Large Panel of Human Tumor Cells and Inhibition of Tumor Growth by GANT61: Implications for Cancer Therapy
Down-Regulation of Gli Transcription Factor Leads to the Inhibition of Migration and Invasion of Ovarian Cancer Cells via Integrin β4-Mediated FAK Signaling | PLOS ONE
![IJMS | Free Full-Text | Hedgehog Signal Inhibitor GANT61 Inhibits the Malignant Behavior of Undifferentiated Hepatocellular Carcinoma Cells by Targeting Non-Canonical GLI Signaling IJMS | Free Full-Text | Hedgehog Signal Inhibitor GANT61 Inhibits the Malignant Behavior of Undifferentiated Hepatocellular Carcinoma Cells by Targeting Non-Canonical GLI Signaling](https://www.mdpi.com/ijms/ijms-21-03126/article_deploy/html/images/ijms-21-03126-g007.png)
IJMS | Free Full-Text | Hedgehog Signal Inhibitor GANT61 Inhibits the Malignant Behavior of Undifferentiated Hepatocellular Carcinoma Cells by Targeting Non-Canonical GLI Signaling
![Schematic representation of the proposed mechanism of GANT61-induced... | Download Scientific Diagram Schematic representation of the proposed mechanism of GANT61-induced... | Download Scientific Diagram](https://www.researchgate.net/publication/270292279/figure/fig8/AS:295184484061185@1447388873040/Schematic-representation-of-the-proposed-mechanism-of-GANT61-induced-apoptosis-in-MMe.png)
Schematic representation of the proposed mechanism of GANT61-induced... | Download Scientific Diagram
![IJMS | Free Full-Text | GANT61 Reduces Hedgehog Molecule (GLI1) Expression and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells IJMS | Free Full-Text | GANT61 Reduces Hedgehog Molecule (GLI1) Expression and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells](https://www.mdpi.com/ijms/ijms-21-06076/article_deploy/html/images/ijms-21-06076-g002.png)
IJMS | Free Full-Text | GANT61 Reduces Hedgehog Molecule (GLI1) Expression and Promotes Apoptosis in Metastatic Oral Squamous Cell Carcinoma Cells
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